16 march 2018

Alzheimer's Drug Trials Keep Failing - It May Be Because We Don't Understand the Disease

(InsideScience)--About a year ago, patients in a clinical trial of a Merck Alzheimer’s drug calledVerubecestat received a phone call from their memory clinics.

“Stop taking the pills and return those left to the clinic immediately,” they were told. The trial has been cancelled.

My wife and about 1,500 Alzheimers patients around the world returned the containers of little blue pills back to their trial physicians.

A statistical analysis of the first three years of thestudyshowed there was no chance the drug would work. The test was costing hundreds of millions of dollars with no hope it would ever help patients or come to market. Another promising anti-Alzheimers drug had failed.

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